Key result
Anticoagulation therapy in solitary atrial flutter patients was associated with a lower ischaemic stroke rate at CHA2DS2-VASc score ≥3 (P<0.05) and improved net clinical outcomes at score ≥4.
Why the study?
Does anticoagulation therapy improve net clinical outcomes in patients with solitary atrial flutter?
Cohort
Yes
Does anticoagulation therapy improve net clinical outcomes in patients with solitary atrial flutter?
p-value: p=<0.05
In solitary atrial flutter, anticoagulation therapy provides a net clinical benefit only in patients with a CHA2DS2-VASc score ≥4, suggesting different risk-benefit thresholds compared to atrial fibrillation.
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Should not yet change practice in solitary atrial flutter; extends evidence for potentially higher CHA2DS2-VASc thresholds than in atrial fibrillation.
Chen et al. (2018) conducted a cohort in Solitary atrial flutter and atrial fibrillation. Anticoagulation therapy vs. No anticoagulation therapy was evaluated on Ischaemic stroke (p=<0.05). Anticoagulation therapy in solitary atrial flutter patients was associated with a lower ischaemic stroke rate at CHA2DS2-VASc score ≥3 (P<0.05) and improved net clinical outcomes at score ≥4.
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