Why the study?
Does autonomic nervous system blockade alter maximal cardiac output during exercise at high altitude in normal subjects?
Population
n=5 normal subjects after 2-week acclimatization at 3,800 m altitude
Comparison
Intravenous propranolol and glycopyrrolate… vs Control and sea level baseline
Design
Other
Authors
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Autonomic blockade does not restore peak cardiac output at altitude; leaves open mechanisms of reduced maximal output in hypoxia.
Does autonomic nervous system blockade alter maximal cardiac output during exercise at high altitude in normal subjects?
Altered autonomic nervous system function affecting heart rate is not the cause of reduced maximal cardiac output at high altitude.
Bogaard et al. (2002) studied this question.