September 1, 1991Journal of Applied Physiology
Hypoxia potentiates exercise-induced sympathetic neural activation in humans
Why the study?
Does rhythmic handgrip exercise during hypoxia increase sympathetic neural activation compared to normoxia in young healthy subjects?
Population
15 young (20-30 yr) healthy subjects
Comparison
Rhythmic handgrip exercise performed during… vs Rhythmic handgrip exercise performed during…
Design
Other
Authors
Discussion
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Member takes
Implication
Hypoxia potentiates sympathetic activation during submaximal exercise in healthy subjects; leaves open relevance to clinical hypoxia or disease.
Structured PICO
Does rhythmic handgrip exercise during hypoxia increase sympathetic neural activation compared to normoxia in young healthy subjects?
P
Population
15 young (20-30 yr) healthy subjects
I
Intervention
Rhythmic handgrip exercise performed during isocapnic hypoxia (inspired O2 concentration of 10%)
C
Comparator
Rhythmic handgrip exercise performed during normoxia
O
Outcome
Lower leg muscle sympathetic nerve activity (MSNA), venous plasma norepinephrine (PNE) concentrations, heart rate, and arterial blood pressuresurrogate
Hypoxia potentiates exercise-induced sympathetic neural activation and heart rate response during rhythmic handgrip exercise in healthy humans.
Cite This Study
Seals et al. (1991) studied this question.