Key result
Treadmill exercise stress testing induced Takotsubo cardiomyopathy characterized by transient global hypokinesis, apical ballooning, and a drop in ejection fraction to 25% in a 62-year-old woman.
Case Report (n=1)
Exercise stress testing can rarely precipitate Takotsubo cardiomyopathy, suggesting alternative stress modalities may be considered in highly susceptible individuals.
Exercise stress testing may precipitate Takotsubo cardiomyopathy; this case leaves open its incidence and clinical relevance.
Noninvasive stress testing is routinely indicated and preferable in the diagnosis of coronary artery disease. We present the case of a patient who developed Takotsubo syndrome/cardiomyopathy (TTS) as a result of an exercise stress echocardiography, as well as a literature review of comparable cases. An abnormal stress test necessitated coronary angiography, which revealed nonobstructive coronaries with apical left ventricular ballooning and a decreased ejection fraction (EF), both of which are concerning for TTS. The patient was medically managed with metoprolol and lisinopril, with improvement in the EF on the follow-up echocardiogram.
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Singh et al. (2023) conducted a case report in Takotsubo Cardiomyopathy (n=1). Treadmill exercise stress test was evaluated on Development of Takotsubo cardiomyopathy (left ventricular apical ballooning and reduced ejection fraction). Treadmill exercise stress testing induced Takotsubo cardiomyopathy characterized by transient global hypokinesis, apical ballooning, and a drop in ejection fraction to 25% in a 62-year-old woman.
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