February 1, 1962Journal of General Microbiology

Isodensity Ultracentrifugation of Foot-and-Mouth Disease Virus in Caesium Chloride

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Population

Foot-and-mouth disease virus (FMDV) in crude infectious fluid

Design

Preclinical

Authors

RTRodes TrautmanThe University of Western Australia SBS. S. BreesePlum Island Animal Disease Center

Discussion

Member takes

Implication

Offers rapid FMDV purification retaining infectivity; leaves open broader validation and scalability.

Structured PICO

Population

Foot-and-mouth disease virus (FMDV) in crude infectious fluid

Intervention

Isodensity ultracentrifugation in a nonlinear Caesium Chloride (CsCl) gradient (1.0 to 1.6 g/ml) for 4 hr at 37,000 rev/min (120,000 g) and 4°C

Outcome

Purification, concentration, and infectivity retention of FMDV

Isodensity ultracentrifugation in a nonlinear CsCl gradient provides a rapid method for purifying and concentrating foot-and-mouth disease virus while retaining infectivity.

Cite This Study

Trautman et al. (1962) studied this question.

synapsesocial.com/papers/6a86d7b3854ced5b0ecf7b67 https://doi.org/10.1099/00221287-27-2-231

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Isodensity Ultracentrifugation of Foot-and-Mouth Disease Virus in Caesium Chloride

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Isodensity Ultracentrifugation of Foot-and-Mouth Disease Virus in Caesium Chloride

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider