Experimental and Clinical Therapeutic Studies on Lymphosarcoma

Article1 November 1948EXPERIMENTAL AND CLINICAL THERAPEUTIC STUDIES ON LYMPHOSARCOMAC. P. RHOADS, F.A.C.P.C. P. RHOADS, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-811 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONIn the entire field of medicine no disorder gives so much concern to physician and layman alike as do the neoplastic diseases of the lymphoid tissue. Of this group, lymphosarcoma is a particularly serious problem. The comparatively intractable nature of the condition, its rapid progress, and the terrifying nature of the associated symptoms, all justify this concern. Especially grave is its tendency to occur in the young.Lymphosarcoma not only presents a therapeutic problem. It also provides for the investigator particularly fascinating and useful experimental material. The tendency of the lesions to be superficial, subject to direct observation, and...Bibliography1. FARBER S: The action of pteroylglutamic conjugates on man, Science, 1947, cvi, 619-621. CrossrefGoogle Scholar2. MALISOFF WM: The action of the endotoxin of Trypanosoma cruzi (KR) on malignant mouse tumors, Science, 1947, cvi, 591-594. CrossrefGoogle Scholar3. KUNDRAT H: Ueber Lympho-Sarkomatosis, Wien. klin. Wchnschr., 1893, vi, 211, 234. Google Scholar4. HELLWIG CA: Malignant lymphoma; the value of radical surgery in selected cases, Surg., Gynec. and Obst., 1947, lxxxiv, 950. Google Scholar5. GALL EA: The surgical treatment of malignant lymphoma, Ann. Surg., 1943, cxviii, 1064. CrossrefGoogle Scholar6. JACKSON H: The classification and prognosis of Hodgkin's disease and allied disorders, Surg., Gynec. and Obst., 1937, lxiv, 465. Google Scholar7. SUGARBAKERCRAVER EDLF: Lymphosarcoma; a study of 196 cases with biopsy, Jr. Am. Med. Assoc., 1940, cxv, 17, 112. Google Scholar8. JACKSONPARKER HF: Hodgkin's disease and allied disorders, 1947, Oxford Univ. Press, New York. Google Scholar9. GARDNERDOUGHERTYWILLIAMS WUTFWL: Lymphoid tumors in mice receiving steroid hormones, Cancer Res., 1944, iv, 73. Google Scholar10. STOUT AP: The results of treatment of lymphosarcoma, New York State Jr. Med., 1947, xlvii, 158. Google Scholar11. LAWRENCESCOTTTUTTLE JHKGLW: Studies on leukemia with the aid of radioactive phosphorus, Internat. Clin., 1939, iii, 33. Google Scholar12. MARINELLI LD: Dosage determination with radioactive isotopes, Am. Jr. Roentgenol., 1942, xlvii, 210. Dosage determination with radioactive isotopes. II. Practical considerations in therapy and protection, Am. Jr. Roentgenol., 1948, lix, 260-280. Google Scholar13. LAWRENCETUTTLESCOTTCONNOR JHLWKGCL: Studies on neoplasms with the aid of radioactive phosphorus. I. The total phosphorus metabolism of normal and leukemic mice, Jr. Clin. Invest., 1940, xix, 267. CrossrefGoogle Scholar14. KENNEYCRAVER JMLF: Further experiences in the treatment of lymphosarcoma with radioactive phosphorus, Radiology, 1942, xxxix, 598. CrossrefGoogle Scholar15. WARREN S: The therapeutic use of radioactive phosphorus, Am. Jr. Med. Sci., 1945, ccix, 701. CrossrefGoogle Scholar16. REINHARDMOOREBIERBAUMMOORE EHCVOSS (a) : Radioactive phosphorus as a therapeutic agent, Jr. Lab. and Clin. Med., 1946, xxxi, 107. (b) REINHARD E. H. WOMACK N. A.: The treatment of blood dyscrasias, lymphomas, and other malignant diseases with radioactive phosphorus: clinical and experimental results, Approaches to Tumor Chemotherapy, Washington, D. C., Am. Assoc. Adv. Sci., 1947, p. 384. Google Scholar17. GILMANPHILIPS AFS: The biological actions and therapeutic applications of β-chloroethyl amines and sulfides, Science, 1946, ciii, 409. CrossrefGoogle Scholar18. JACOBSONSPURRBARRONSMITHLUSHBAUGHDICK LOCLESTCGF: Nitrogen mustard therapy; studies on the effect of methyl-bis (Beta-chloroethyl) amine hydrochloride on neoplastic diseases and allied disorders of the hemopoietic system, Jr. Am. Med. Assoc., 1946, cxxxii, 263. CrossrefGoogle Scholar19. SHEPPARDWELLSHAHNGOODELL CWEBPFJP: Studies of the distribution of intravenously administered colloidal sols of manganese dioxide and gold in human beings and dogs using radioactive isotopes, Jr. Lab. and Clin. Med., 1947, xxxii, 274. Google Scholar20. PATERSONHADDOWAP THOMASWATKINSON EAIJM: Leukaemia treated with urethane compared with deep x-ray therapy, Lancet, 1946, i, 677. CrossrefGoogle Scholar21. HUGGINSYÜJONES CSTR: Inhibitory effects of ethyl carbamate on prostatic cancer, Science, 1947, cvi, 147. CrossrefGoogle Scholar22. BRUESSHEAR AMMJ: Chemical treatment of tumors. X. Reactions of four patients with advanced malignant tumors to injection of a polysaccharide from Serratia marcescens culture filtrate, Jr. Nat. Cancer Inst., 1944, v, 195. Google Scholar23. KOPAC MJ: Some cellular and surface chemical aspects of tumor chemotherapy, Approaches to Tumor Chemotherapy, Washington, D. C., Am. Assoc. Adv. Sci., 1947, p. 27. Google Scholar24. HEILMANKENDALL FREC: The influence of 11-dehydro-17-hydroxycorticosterone (compound E) on the growth of a malignant tumor in the mouse, Endocrinology, 1944, xxxiv, 416. CrossrefGoogle Scholar25. MURPHYSTURM JBE (a) : The effect of adrenal cortical and pituitary adrenotropic hormones on transplanted leukemia in rats, Science, 1944, xcix, 303. (b) MURPHY J. B. STURM E.: The transmission of an induced lymphatic leukemia and lymphosarcoma in the rat, Cancer Res., 1941, i, 379. CrossrefGoogle Scholar26. STOERCK HC: The regression of lymphosarcoma implants in pyridoxine-deficient mice, Jr. Biol. Chem., 1947, clxxi, 437. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented at the Twenty-Ninth Annual Session of the American College of Physicians, San Francisco, California, April 21, 1948. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Mediastinaltumoren und ihre chirurgische Bedeutung 1 November 1948Volume 29, Issue 5Page: 811-821KeywordsLesionsLymphoid tissue ePublished: 1 December 2008 Issue Published: 1 November 1948 PDF downloadLoading ...