A practical approach to immunocompromised surgical patients involves determining risk, aggressive diagnosis, early therapy, and high suspicion for infectious complications.
Offers pragmatic framework for immunocompromised surgical patients; leaves open need for prospective validation.
Immunocompromised patients are increasingly common in modern surgical practice. Challenges related to their care include identifying the determinants of increased risk and selecting the appropriate therapy for individual patients. There are multiple and overlapping causes of immunosuppression in surgical patients that make the interpretation of clinical trials difficult. A clear understanding of these mechanisms guides the physician to choose the immunomodulatory agents that can be used for improving current rates of complication and mortality. The best practical approach to immunocompromised patients involves determining who is at risk, aggressive diagnosis, early therapy, and a high index of suspicion for infectious complications.
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Yee et al. (1993) studied this question.
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