Why the study?
Do conduction defects and ventricular arrhythmias predict late sudden death in patients after surgical closure of a ventricular septal defect?
Population
187 patients who had surgical closure of a ventricular septal defect between 1958 and 1975
Design
Cohort
Follow-up
up to 21 years
Authors
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May warrant enhanced post-VSD closure surveillance; leaves open need for prospective validation and intervention trials.
Do conduction defects and ventricular arrhythmias predict late sudden death in patients after surgical closure of a ventricular septal defect?
Ventricular arrhythmias and conduction defects, particularly transient complete heart block, are major risk factors for late sudden death up to 21 years after surgical closure of ventricular septal defects.
Blake et al. (1982) studied this question.
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