Key result
Finite element analysis of a novel self-expanding aortic valve stent demonstrated a maximum von Mises stress of 0.26 MPa at the leaflet base and small radial (0.18 mm) and axial (0.26 mm) deformations.
Why the study?
Engineering design optimization challenges affecting long-term valve durability remain due to the complex anatomical location between the left ventricle and aorta.
A novel self-expanding aortic valve stent design demonstrated favorable biomechanical properties in a finite element analysis, with minimal deformations and acceptable stress distribution.
Hypothesis-generating for the novel stent's mechanical stability; prospective studies needed before clinical consideration.
Worldwide, one of the leading causes of death for patients with cardiovascular disease is aortic valve failure or insufficiency as a result of calcification and cardiovascular disease. The surgical treatment consists of repair or total replacement of the aortic valve. Artificial aortic valve implantation via a percutaneous or endovascular procedure is the minimally invasive alternative to open chest surgery, and the only option for high-risk or older patients. Due to the complex anatomical location between the left ventricle and the aorta, there are still engineering design optimization challenges which influence the long-term durability of the valve. In this study we developed a computer model and performed a numerical analysis of an original self-expanding stent for transcatheter aortic valve in order to optimize its design and materials. The study demonstrates the current valve design could be a good alternative to the existing commercially available valve devices.
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Castravete et al. (2020) studied Aortic valve failure. Novel self-expanding aortic valve stent (computational model) was evaluated on Stress distribution and radial/axial deformations. Finite element analysis of a novel self-expanding aortic valve stent demonstrated a maximum von Mises stress of 0.26 MPa at the leaflet base and small radial (0.18 mm) and axial (0.26 mm) deformations.
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