Key result
A novel heart valve stent design was shown theoretically and experimentally to maintain the compliance of the aortic root close to native root values.
A novel heart valve stent design preserves the natural compliance of the aortic root in theoretical and experimental models, potentially reducing tissue trauma compared to standard stents.
Hypothesis-generating for compliant valve stents; human trials needed before clinical consideration.
Percutaneous aortic valve implantation has become an alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Vascular stents clinically used today for non-invasive aortic valve replacement tend, however, to impede the dimension changes of the compliant aortic root over the cardiac cycle. The purpose of the present work is to assess the influence of a novel heart valve stent, designed specifically to limit the traumatism in tissue, on the compliance of the aortic root. A theoretical approach is adopted to model the mechanical behaviour of the different stent parts and assess the compliance modification induced by the stent. The validity of the model is then tested experimentally. Both approaches show that the specific geometry of the stent makes it possible to keep the compliance of the aortic root close to the native root values.
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Heim et al. (2011) studied Aortic valve replacement. Novel heart valve stent vs. Native root values was evaluated on Compliance of the aortic root. A novel heart valve stent design was shown theoretically and experimentally to maintain the compliance of the aortic root close to native root values.
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