Key result
A brain biopsy was identified as a novel trigger for reverse Takotsubo cardiomyopathy in a single patient case.
Why the study?
Reverse Takotsubo cardiomyopathy is associated with neurologic conditions, but a case specifically following brain biopsy had not been previously reported.
Case Report (n=1)
This report presents the first documented case of reverse Takotsubo cardiomyopathy triggered by a brain biopsy.
May prompt vigilance for reverse Takotsubo after brain procedures; single-case report leaves open broader applicability.
Reverse Takotsubo cardiomyopathy (rTTC) is a variant of Takotsubo cardiomyopathy (TTC) or stress-induced cardiomyopathy. TTC is a transient cardiomyopathy resulting in a heart failure syndrome, triggered by emotional and/or physical stressors, that is usually self-limited. rTTC is characterized by basal wall hypokinesis and apical wall hyperkinesis, the opposite of TTC. rTTC is more commonly associated with neurologic conditions, most notably intracranial hemorrhage. We present the first case in the literature of rTTC specifically following brain biopsy.
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Ives et al. (2020) conducted a case report in Reverse Takotsubo cardiomyopathy (n=1). Brain biopsy was evaluated on Reverse Takotsubo cardiomyopathy. A brain biopsy was identified as a novel trigger for reverse Takotsubo cardiomyopathy in a single patient case.
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