Acute global cardiac decompensation due to inverted takotsubo cardiomyopathy after skull–brain trauma—A case report

Takotsubo cardiomyopathy (TTC) usually occurs in postmenopausal women after acute physical or mental stress and typically presents with apical ballooning of the left ventricle. TTC manifests with symptoms similar to acute coronary syndrome and may be accompanied by ECG changes, so coronary angiography is mandatory to exclude acute coronary syndrome. Other forms of TTC with atypical mid-ventricular ballooning have been described. Severe cerebral damage may also go along with ECG changes such as ST segment elevation, release of cardiac enzymes and/or cardiac dysfunction and often presents similar to TTC. For that reason a recent review postulates a pathophysiological relationship between TTC and cardiac dysfunction after cerebral bleeding.