Severe head injury can act as a physical stressor triggering an atypical form of Takotsubo cardiomyopathy.
Hypothesis-generating for head injury triggering inverted Takotsubo; larger studies needed before clinical implications.
Takotsubo cardiomyopathy or "apical ballooning syndrome" is characterized by an acute onset of transient akinesia of the apical portion of the left ventricle accompanied by electrocardiographic changes and minimal myocardial enzymatic release mimicking acute myocardial infarction without significant stenosis on the coronary angiogram. Emotional or physical stress might trigger this reversible form of cardiomyopathy. We describe a case of a 22-year-old woman presenting with an atypical form of Takotsubo cardiomyopathy after severe head injury.
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Sagrera et al. (2010) studied this question.
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