Key result
Optical coherence tomography was utilized in a case of dobutamine stress echocardiography-induced Takotsubo cardiomyopathy to exclude vessel alterations and clarify pathophysiology.
Case Report (n=1)
Optical coherence tomography can be used to exclude vessel alterations and clarify mechanisms in DSE-induced Takotsubo cardiomyopathy.
OCT may exclude coronary changes in rare DSE-induced Takotsubo; hypothesis-generating case report requiring prospective validation.
Takotsubo cardiomyopathy is a clinical disorder characterized by a transient dilatation and akynesis or dyskinesis of the left ventricular (LV) apex, mimicking an anterior wall acute myocardial infarction in the absence of significant coronary artery disease (CAD). It typically occurs during an episode of severe emotional or physical stress. Recent reports suggested the potential of dobutamine stress echocardiography (DSE) in inducing the aforementioned syndrome. The transient dysfunction of the LV does not fit any known coronary distribution. Furthermore, there is no obstructive CAD demonstrated at angiography to account for the observed dysfunction. Consequently, the pathophysiology of this syndrome is still undetermined. Here, we report a case of DSE-induced Takotsubo cardiomyopathy in which high-resolution intracoronary imaging was utilized to exclude possible vessel alterations to help provide potential mechanistic explanations for the development of this condition.
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Fineschi et al. (2013) conducted a case report in Takotsubo cardiomyopathy (n=1). Optical Coherence Tomography was evaluated on Vessel alterations. Optical coherence tomography was utilized in a case of dobutamine stress echocardiography-induced Takotsubo cardiomyopathy to exclude vessel alterations and clarify pathophysiology.
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