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May 2, 1998BMJOpen Access

North of England evidence based development project: guideline for angiotensin converting enzyme inhibitors in primary care management of adults with symptomatic heart failure

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Why the study?

Does angiotensin converting enzyme inhibitor therapy improve outcomes in adults with symptomatic heart failure in primary care?

Population

Adults with symptomatic heart failure and evidence of impaired left ventricular function, or recent…

Design

Guideline

Authors

Nick Freemantle
Nick FreemantleHeart Failure & Transplant
JMJames MasonCentral and North West London NHS Foundation Trust

Discussion

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Overview

Supports ACE inhibitor initiation in primary care for symptomatic HF with impaired LV function; confirms RCT benefits in Level 1 guidelines.

Structured PICO

Does angiotensin converting enzyme inhibitor therapy improve outcomes in adults with symptomatic heart failure in primary care?

P
Population
Adults with symptomatic heart failure and evidence of impaired left ventricular function, or recent myocardial infarction with impaired left ventricular function, attending general practice.
I
Intervention
Angiotensin converting enzyme (ACE) inhibitors

This guideline recommends that all adult patients with symptomatic heart failure and impaired left ventricular function should be prescribed an ACE inhibitor in primary care.

Cite This Study

Freemantle et al. (1998) studied this question.

synapsesocial.com/papers/6a86e0e86fbb37794f7cb0fdhttps://doi.org/10.1136/bmj.316.7141.1369

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of converting enzyme inhibition on progression of chronic heart failure: results of the Munich Mild Heart Failure Trial.1992 · 119 citations
  2. 2Evidence of inadequate investigation and treatment of patients with heart failure.1994 · 196 citations
  3. 3Contrasting peripheral short-term and long-term effects of converting enzyme inhibition in patients with congestive heart failure. A double-blind, placebo-controlled trial.1989 · 240 citations
  4. 4Influence of angiotensin converting enzyme inhibition on exercise performance and clinical symptoms in chronic heart failure: a multicentre, double-blind, placebo-controlled trial1993 · 24 citations
  5. 5Comparative Effects of Long-Term Therapy with Captopril and Ibopamine in Chronic Congestive Heart Failure in Old Patients2008 · 35 citations