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Cytokines play a pleiotropic role in atherogenesis, and the ratio of pro- and anti-inflammatory cytokines may serve as a promising predictor for atherosclerotic plaque instability and adverse cardiovascular events.
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Cytokines play a complex, pleiotropic role in atherosclerosis and plaque destabilization, and while they hold promise as biomarkers for predicting recurrent cardiovascular events, their clinical application requires further clarification.
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Prudnikov et al. (2018) conducted a review in Unstable atherosclerotic plaque. Cytokines was evaluated. Cytokines play a pleiotropic role in atherogenesis, and the ratio of pro- and anti-inflammatory cytokines may serve as a promising predictor for atherosclerotic plaque instability and adverse cardiovascular events.
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