Key result
Very early postoperative abnormal troponin was associated with a 41.7% rate of cardiovascular events at one month compared to 9.9% with normal troponin (p < 0.0001).
Why the study?
The prognostic meaning of very early (<6 h) troponin increase after noncardiac surgery in patients with a suspected cardiac event was not established.
Does very early troponin increase predict cardiovascular events in patients admitted to the recovery room after noncardiac surgery with suspected cardiac events?
Observational (n=296)
Does very early troponin increase predict cardiovascular events in patients admitted to the recovery room after noncardiac surgery with suspected cardiac events?
Effect estimate: two-fold risk
Absolute Event Rate: 41.7% vs 9.9%
p-value: p=< 0.0001
Very early troponin measurement (<6 h) after noncardiac surgery in patients with suspected cardiac events helps identify those at high risk for cardiovascular death, MI, or heart failure at one month.
May aid postoperative risk stratification; hypothesis-generating and should not yet change practice.
We assessed the prognostic meaning of very early (<6 h) troponin increase after noncardiac surgery in a population of patients admitted to the recovery room, for whom troponin measurements were taken because of a suspected cardiac event. Among a total of 296 patients, abnormal troponin was found in 24 (8.1%). Ten patients in this group (41.7%) and 27 among those with normal troponin (9.9%) experienced cardiovascular death, myocardial infarction, or decompensated heart failure at one month (p < 0.0001). Troponin was independently associated with a two-fold risk of events (p < 0.0001). In these patients, very early troponin measurement in the recovery room may help to identify patients at risk of cardiovascular events.
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Conti et al. (2020) conducted an observational in Suspected cardiac events after noncardiac surgery (n=296). Very early (<6 h) abnormal troponin increase vs. Normal troponin was evaluated on Cardiovascular death, myocardial infarction, or decompensated heart failure at one month (two-fold risk, p=< 0.0001). Very early postoperative abnormal troponin was associated with a 41.7% rate of cardiovascular events at one month compared to 9.9% with normal troponin (p < 0.0001).
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