March 31, 2015Organic Letters

Design, Synthesis, and Characterization of SO₂-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery

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Abstract

A set of novel SO2-containing azabicyclo[3.n.1]alkanes has been synthesized by the double-Mannich annulation of of the corresponding monocyclic S-ketones. These compounds have been rationally designed as 3D-shaped, conformationally restricted SO2-containing building blocks for drug discovery.

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Druzhenko et al. (2015) studied this question.

synapsesocial.com/papers/6a86e297a6ddb97d43d3c135 https://doi.org/10.1021/acs.orglett.5b00608

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Design, Synthesis, and Characterization of SO₂-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery

Abstract

Discussion

Cite This Study

Design, Synthesis, and Characterization of SO₂-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery

Abstract

Discussion

Cite This Study

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