Die sterische Einheitlichkeit des synthetischen Val⁵‐Hypertensin II‐Asp¹‐β‐amids

The enzymatic degradation of synthetic Val 5 ‐Hypertensin II‐Asp 1 ‐β‐amide with trypsin, chymotrypsin, pepsin, subtilisin, carboxypeptidase and leucineaminopeptidase is described, proving the optical purity of all amino‐acid residues ( L ‐configuration) except His 6 . The configuration of this amino‐acid has been confirmed by its quantitative destruction with L ‐amino‐acid oxidase in hydrolysates.