Key result
Laryngeal mask airway-supreme provided satisfactory ventilation and surgical conditions without neuromuscular blockers during laparoscopic gynecological surgery, with a significantly lower oropharyngeal leak pressure (25.6 vs 39.5 cmH2O, p<0.001) compared to endotracheal tube.
Why the study?
New generation supraglottic airway devices are suitable for many laparoscopic surgeries, but ventilation parameters and surgical view needed evaluation without neuromuscular blockers.
Does the use of a laryngeal mask airway-supreme compared to an endotracheal tube provide adequate ventilation and surgical conditions without neuromuscular blockers in patients undergoing laparoscopic gynecological surgery?
RCT (n=100)
Double-blind
Block randomization
No
Does the use of a laryngeal mask airway-supreme compared to an endotracheal tube provide adequate ventilation and surgical conditions without neuromuscular blockers in patients undergoing laparoscopic gynecological surgery?
Absolute Event Rate: 25.6% vs 39.5%
p-value: p=<0.001
Laparoscopic gynecological surgeries can be safely performed without neuromuscular blockers using either a laryngeal mask airway-supreme or an endotracheal tube, though the supraglottic device offers easier gastric tube insertion and fewer early postoperative pharyngolaryngeal symptoms.
LM-S without NMB may be feasible in laparoscopic gynecological surgery; leaves open confirmation versus ETT in larger trials.
New generation supraglottic airway devices are suitable for airway management in many laparoscopic surgeries. In this study, we evaluated and compared the ventilation parameters of the laryngeal mask airway-supreme (LM-S) and endotracheal tube (ETT) when a neuromuscular blocker (NMB) agent was not used during laparoscopic gynecological surgery. The second outcome was based on the evaluation of the surgical view because it may affect the surgical procedure.This was a randomized study that enrolled 100 patients between 18 and 65 years old with an ASA I-II classification. Patients were divided into 2 groups: Group ETT and Group LM-S. Standard anesthesia and ventilation protocols were administered to patients in each group. Ventilation parameters [airway peak pressure (Ppeak), mean airway pressure (Pmean), total volume, and oropharyngeal leak pressure] were recorded before, after, and during peritoneal insufflation and before desufflation, as well as after the removal of the airway device. Perioperative surgical view quality and the adequacy of the pneumoperitoneum were also recorded.The data of 100 patients were included in the statistical analysis. The Ppeak values in Group ETT were significantly higher in the second minute after airway device insertion. The Ppeak and Pmean values in Group ETT were significantly higher before desufflation and after removal of the airway device. No significant differences were found between the groups in terms of adequacy of the pneumoperitoneum or quality of the surgical view.The results of this study showed that gynecological laparoscopies can be performed without using a NMB. Satisfactory conditions for ventilation and surgery can be achieved while sparing the use of muscle relaxants in both groups despite the Trendelenburg position and the pneumoperitoneum of the patients, which are typical for laparoscopic gynecological surgery. The results are of clinical significance because they show that the use of a muscle relaxant is unnecessary when supraglottic airways are used for these surgical procedures.
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Özbilgin et al. (2021) conducted an RCT in Laparoscopic gynecological surgery (n=100). Laryngeal mask airway-supreme (LM-S) vs. Endotracheal tube (ETT) was evaluated on Oropharyngeal leak pressure (cmH2O) (p=<0.001). Laryngeal mask airway-supreme provided satisfactory ventilation and surgical conditions without neuromuscular blockers during laparoscopic gynecological surgery, with a significantly lower oropharyngeal leak pressure (25.6 vs 39.5 cmH2O, p<0.001) compared to endotracheal tube.
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