Key result
Two-dimensional speckle tracking imaging of right ventricular free wall longitudinal strain detected early systolic function changes with greater sensitivity than standard measures (p<0.05).
Why the study?
The study was conducted to understand changes in right ventricular function in patients with pulmonary hypertension.
Does two-dimensional speckle tracking imaging (longitudinal strain) improve the detection of early right ventricular systolic function changes compared to standard echocardiographic measures in patients with pulmonary hypertension?
Observational (n=74)
Does two-dimensional speckle tracking imaging (longitudinal strain) improve the detection of early right ventricular systolic function changes compared to standard echocardiographic measures in patients with pulmonary hypertension?
p-value: p=<0.05
Right ventricular free wall longitudinal strain measured by two-dimensional speckle tracking is more sensitive than standard echocardiographic parameters for detecting early right ventricular systolic dysfunction in patients with mild pulmonary hypertension.
May inform noninvasive RV monitoring in PH; hypothesis-generating and should not yet change practice.
Objective: To realize the changes in pulmonary hypertension (PH) patients’ right ventricular function.Methods: A total number of 74 patients with PH were included, and the parameters of standard echocardiographic were measured as well as the strain of peak longitudinal of each segment during the systole of the right ventricle to calculate the global longitudinal strain (LS) during systole of the right ventricular free wall.Results: ① As pulmonary arterial pressure increased, the right ventricular area gradually increased, and the case group showed the decreased right ventricular fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), and tricuspid annular peak systolic velocity (S’) (p < 0.05). They, RVFAC, and TAPSE depicted significant differences that were statistical (p < 0.05) from the other groups. ② With increasing pulmonary arterial pressure, the right ventricular free wall’s LS gradually reduced (p < 0.05).Conclusion: ① LS right ventricular free wall is useful in detecting changes in right ventricular systolic function early on with greater sensitivity than RVFAC, TAPSE, and S’. In addition, increased right ventricular pressure loading can result in a subsequent impairment of right ventricular myocardial mechanics. ② As right ventricular pressure loading increases, right ventricular strain decreases. ③ In mild PH, the right ventricular free wall’s. LS is more sensitive than standard measures in spotting early alterations in myocardial mechanics.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2023) conducted an observational in Pulmonary hypertension (n=74). Two-dimensional speckle tracking imaging (longitudinal strain) vs. Standard echocardiographic measures (RVFAC, TAPSE, S') was evaluated on Right ventricular free wall longitudinal strain (LS) and standard echocardiographic parameters (p=<0.05). Two-dimensional speckle tracking imaging of right ventricular free wall longitudinal strain detected early systolic function changes with greater sensitivity than standard measures (p<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: