Key result
Elderly patients (≥65 years) undergoing surgery for left-sided native valve infective endocarditis had a significantly higher in-hospital mortality rate compared to non-elderly patients (26.3% vs. 5.7%, P=0.001).
Why the study?
The short- and mid-term outcomes of elderly patients undergoing surgery for left-sided native valve infective endocarditis were not clearly defined.
Does advanced age (≥65 years) worsen outcomes in patients undergoing surgery for left-sided native valve infective endocarditis?
Population
179 patients undergoing surgical treatment for active LSNIE at a single institution
Comparison
Elderly (≥65 years) vs non-elderly (<65 years) patients
Design
Single-center retrospective study
Follow-up
3 years
Authors
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Supports cautious surgical decision-making in elderly left-sided IE; leaves open whether frailty tools refine risk prediction.
Cohort (n=179)
No
Does advanced age (≥65 years) worsen outcomes in patients undergoing surgery for left-sided native valve infective endocarditis?
Absolute Event Rate: 26.3% vs 5.7%
p-value: p=0.001
Elderly patients undergoing surgery for left-sided native valve infective endocarditis face higher in-hospital mortality, but those surviving to discharge have mid-term survival comparable to younger patients.
Lin et al. (2020) conducted a cohort in Left-sided native valve infective endocarditis (n=179). Advanced age (≥65 years) vs. Age <65 years was evaluated on In-hospital mortality (p=0.001). Elderly patients (≥65 years) undergoing surgery for left-sided native valve infective endocarditis had a significantly higher in-hospital mortality rate compared to non-elderly patients (26.3% vs. 5.7%, P=0.001).
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