Answers are grounded in this paper and cite their sources.
Acid and alkaline products must usually be diluted before patch testing in order to be non-irritant. The use of ordinary solvents for the dilution often means low-concentration products to be tested. By using buffer solutions, the possible test concentrations can be increased at least many hundred fold.
No takes yet. Share an insight, caveat, or question.
M. Bruze (1984) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: