Key result
Adeno-associated virus-based transgene delivery provides a potential long-term and safe therapeutic approach for treating progressive vascular diseases.
Population
Patients with Progressive Vascular Diseases (PVD)
Design
Review
Authors
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Supports AAV gene therapy exploration in vascular disease; leaves open validation in prospective trials.
AAV-based gene therapy delivering anti-inflammatory, lipoprotein metabolism, or anti-oxidant genes represents a potential long-term treatment strategy for progressive vascular diseases.
Paul L. Hermonat (2014) conducted a review in Progressive Vascular Diseases. Adeno-Associated Virus-Based Transgene Delivery was evaluated. Adeno-associated virus-based transgene delivery provides a potential long-term and safe therapeutic approach for treating progressive vascular diseases.
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