Key result
The mean 15D index value for the Hungarian adult general population was 0.810, with 78.7% of respondents reporting problems in at least one health domain.
Why the study?
The study was conducted to establish population norms for the 15D generic preference-accompanied health status measure in Hungary.
Cross-Sectional (n=2,000)
This study establishes the first population norms for the 15D health status measure in Hungary, providing a benchmark for evaluating disease burden and efficacy outcomes.
Hungarian 15D norms now available; leaves open clinical adoption pending prospective validation.
OBJECTIVES: 15D is a generic preference-accompanied health status measure covering a wide range of health areas, including sensory functions. The aim of this study was to establish population norms for the 15D instrument in Hungary. METHODS: 2000 members of the Hungarian adult general population participated in an online cross-sectional survey in August 2021. The sample was broadly representative in terms of gender, age groups, highest level of education, geographical region, and settlement type. Index values were derived using the Norwegian 15D value set. In addition to providing population norms, mean index values were computed for 32 physical and 24 mental health condition groups. RESULTS: Most respondents (78.7%) reported problems in at least one 15D domain. The most problems were reported with sleeping (50.7%), followed by vitality (49.2%), distress (43.6%), discomfort and symptoms (31.2%), depression (31.1%), sexual activities (29.6%), breathing (28.1%), and vision (27.8%). The mean 15D index value was 0.810. With advancing age categories, the 15D index values showed an inverse U-shaped curve. Generally, mean index values in respondents with mental health conditions were lower [range 0.299 (post-traumatic stress disorder) to 0.757 (smoking addiction)] than those of respondents with physical conditions [range 0.557 (liver cirrhosis) to 0.764 (allergies)]. CONCLUSIONS: This study provided 15D population norms of the Hungarian general population; furthermore, this is the first study to provide population norms for the 15D in any country. The values established in this study can serve as benchmarks for evaluating efficacy outcomes in clinical trials, quantifying disease burden and identifying unmet needs.
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Nikl et al. (2023) conducted a cross-sectional in General population health status (n=2,000). General population health status was evaluated on Mean 15D index value (95% CI 0.800-0.819). The mean 15D index value for the Hungarian adult general population was 0.810, with 78.7% of respondents reporting problems in at least one health domain.
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