Second-generation antisense oligonucleotides: structure—activity relationships and the design of improved signal-transduction inhibitors

Conference Article| August 01 1996 Second-generation antisense oligonucleotides: structure—activity relationships and the design of improved signal-transduction inhibitors K.-H. Altmann; K.-H. Altmann *Ciba-Geigy Ltd., Central Research Laboratories, R-1060.2.34, CH-4002 Basel, Switzerland Search for other works by this author on: This Site PubMed Google Scholar D. Fabbro; D. Fabbro †Ciba-Geigy Ltd., Pharmaceutical Division, Department of Oncology, CH-4002 Basel, Switzerland Search for other works by this author on: This Site PubMed Google Scholar N. M. Dean; N. M. Dean ‡ISIS Pharmaceuticals, Department of Molecular Pharmacology, 2280 Faraday Avenue, Carlsbad, CA 92008, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar T. Geiger; T. Geiger †Ciba-Geigy Ltd., Pharmaceutical Division, Department of Oncology, CH-4002 Basel, Switzerland Search for other works by this author on: This Site PubMed Google Scholar B. P. Monia; B. P. Monia ‡ISIS Pharmaceuticals, Department of Molecular Pharmacology, 2280 Faraday Avenue, Carlsbad, CA 92008, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar M. Müllert; M. Müllert †Ciba-Geigy Ltd., Pharmaceutical Division, Department of Oncology, CH-4002 Basel, Switzerland Search for other works by this author on: This Site PubMed Google Scholar P. Nicklin P. Nicklin §Ciba Geigy Ltd., Pharmaceutical Division, Department of Toxicology, Horsham, West Sussex RH12 4AB, U.K. Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Received: March 20 1996 Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1996 Biochemical Society1996 Biochem Soc Trans (1996) 24 (3): 630–637. https://doi.org/10.1042/bst0240630 Article history Received: March 20 1996 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation K.-H. Altmann, D. Fabbro, N. M. Dean, T. Geiger, B. P. Monia, M. Müllert, P. Nicklin; Second-generation antisense oligonucleotides: structure—activity relationships and the design of improved signal-transduction inhibitors. Biochem Soc Trans 1 August 1996; 24 (3): 630–637. doi: https://doi.org/10.1042/bst0240630 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: PS-ODN, phosphorothioate oligodeoxynucleotide, PKC, protein kinase C This content is only available as a PDF.