Chemical synthesis study demonstrates gold-catalyzed [4+2] annulations of dienes with nitrosoarenes, indicating a new catalytic route for nitroso-Povarov reactions.
This work reports the first success of the nitroso‐Povarov reaction, involving gold‐catalyzed [4+2] annulations of nitrsoarenes with substituted cyclopentadienes. In this catalytic sequence, nitrosoarenes presumably attack gold‐π‐dienes by a 1,4‐addition pathway, generating allylgold nitrosonium intermediates to complete an intramolecular cyclization. Acyclic dienes are also applicable substrates, and affording oxidative nitroso‐Povarov products.
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Chen et al. (2019) studied this question.
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