Population
16 human anti-Sm sera and 15 human anti-RNP sera from patients with systemic autoimmune diseases, two mouse…
Design
Preclinical
Authors
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May refine autoantibody specificity testing in SLE; leaves open pathogenic roles of epitope localization.
The study maps the specific antigenic determinants of Sm and U1 RNP particles recognized by autoimmune sera and identifies their distinct subcellular localizations.
Habets et al. (1985) studied this question.
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