Key result
Prediabetes in patients with coronary artery disease was associated with similar rates of cardiac events compared to normal glucose tolerance in the ARTEMIS study.
Why the study?
Do patients with coronary artery disease and prediabetes have a higher risk of cardiac events compared to those with normal glucose tolerance?
Do patients with coronary artery disease and prediabetes have a higher risk of cardiac events compared to those with normal glucose tolerance?
Answers are grounded in this paper and cite their sources.
This editorial highlights that the ARTEMIS study's finding of similar cardiac event rates between prediabetes and normal glucose tolerance in CAD patients may be driven by the selection of a low-risk population.
We read with interest the results of the Innovation to Reduce Cardiovascular Complications of Diabetes at the Intersection (ARTEMIS) study (1). The authors conclude that cardiac events in patients with coronary artery disease and prediabetes (revascularized or medically treated) were similar to those in patients with normal glucose tolerance. The study includes a rather low-risk population with prediabetes. About 46% of patients had stable angina (patients who have very low event rates), and the rest had remote acute coronary syndrome (ACS). Recruitment 3–6 months after the coronary angiography with or without revascularization excluded the highest-risk ACS patients who are expected to have events early. Without the baseline Global Registry of Acute Coronary Events (GRACE) or Thrombolysis …
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Chattopadhyay et al. (2019) conducted a letter in Coronary artery disease and prediabetes. Prediabetes vs. Normal glucose tolerance was evaluated on Cardiac events. Prediabetes in patients with coronary artery disease was associated with similar rates of cardiac events compared to normal glucose tolerance in the ARTEMIS study.
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