Why the study?
Does discontinuation of hydantoin therapy improve progressive encephalopathy in patients with chronic hydantoin intoxication?
Population
10 patients receiving long-term hydantoin therapy with progressive neurological deterioration
Design
Case_series
Authors
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May support reversibility of hydantoin encephalopathy in cases; leaves open need for controlled confirmation before practice change.
Does discontinuation of hydantoin therapy improve progressive encephalopathy in patients with chronic hydantoin intoxication?
Chronic hydantoin intoxication can cause severe, progressive encephalopathy that is reversible upon discontinuation of the drug.
Josefina M. Vallarta (1974) studied this question.
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