Human Case ofRickettsia felisInfection, Taiwan

cattle sera (1,3), we cannot exclude the possibility that the S-1-HUN-like kobuvirus can cause viremia (and generalized infection) in swine. S-1-HUN-like virus may typically cause asymptomatic infections in swine. However, epidemiologic and molecular studies are required regarding the importance of this virus as a causative agent of some diseases of domestic pigs and related animals. Sequence analysis of the complete nucleotide and amino acid sequences of coding (L, P1, P2, and P3: 7,467 nt) and noncoding regions and the genetic organization strain indicate that S-1-HUN is a typical kobuvirus. Phylogenetic analysis shows that S-1 -HUN strain is genetically included in the genus Kobuvirus but is distinct from Aichi and bovine kobuviruses. Porcine kobuvirus strain S-1-HUN is a candidate for a new, third species of the genus Kobuvirus.