Acute reocclusion during interventions for myocardial infarction can often be reversed with additional therapy but is associated with a trend toward higher rates of subsequent reinfarction.
Reocclusion may raise reinfarction risk after MI intervention; leaves open whether angioplasty reduces events versus thrombolysis in contemporary cohorts.
Acute reocclusion of the recanalized infarcted vessel was observed during thrombolytic therapy in 28 or 138 patients, and during angioplasty following thrombolysis in 5 of 70 patients. The occluded vessel reopened again in 20 of 28 patients by additional administration in nitroglycerin and urokinase and in 3 of 5 patients by repeated angioplasty. There was no significant difference in success rate of thrombolysis or angioplasty between patients with acute reocclusion and those without. However, reinfarction after acute intervention tended to be more common in the former patients than the latters.
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Hattori et al. (1988) studied this question.
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