Key result
Radial applanation pulse wave analysis for measuring AIX-75 in pregnancy showed high observer agreement, with a between-observer mean difference of 0.1 ± 11.0.
Why the study?
Can aortic augmentation index (AIX-75) be reliably measured by nurses using pulse wave analysis in pregnant women?
Cross-Sectional (n=20)
Observer-blinded
No
Can aortic augmentation index (AIX-75) be reliably measured by nurses using pulse wave analysis in pregnant women?
Aortic augmentation index (AIX-75) can be reliably measured by nurses using pulse wave analysis in pregnant women, demonstrating high observer agreement.
Answers are grounded in this paper and cite their sources.
Supports nurse-performed AIX-75 assessment in pregnancy; leaves open its prognostic role or integration into hypertensive care.
OBJECTIVE: To estimate clinical agreement in relation to measuring aortic augmentation index (AIX-75) in pregnancy in a routine clinical setting. METHODS: A hospital-based clinical agreement study of 20 women in which two trained nurses alternated in measuring arterial function (AIX standardized to a heart rate of 75 beats-per-minute, AIX-75) on a single occasion in triplicate, after participants had rested semi-recumbent for 15 min. Right brachial blood pressure (BP) was measured using the Microlife 3BTO-A oscillometric device. Radial applanation pulse wave analysis (PWA) was undertaken according to current guidelines using the SphygmoCor device with a hand-held Millar tonometer applanated at the right radial artery. Each nurse was blinded to others PWA results. Observer agreement was assessed using the Bland-Altman "limits of agreement" (LOA, mean difference ±2 SD) approach. RESULTS: Median gestation was 37 weeks (range: 12-42), mean age 31 years, 30% nulliparous, mean brachial BP 128/79 mm Hg. Based on all six PWA measurements, mean AIX-75 was 11.7 (range: -18 to +35). The between-observer LOA was 0.1 ± 11.0 and the within-observer LOA's were 1 ± 10 and -2 ± 8 for the two nurses. Observer differences did not vary systematically with the magnitude of AIX-75. CONCLUSION: AIX-75 can be measured by nurses using PWA in pregnancy with a high level of observer agreement.
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Crilly et al. (2014) conducted a cross-sectional in Pregnancy (n=20). Radial applanation pulse wave analysis (PWA) was evaluated on Between-observer agreement (limits of agreement) for AIX-75 (LOA 0.1 ± 11.0). Radial applanation pulse wave analysis for measuring AIX-75 in pregnancy showed high observer agreement, with a between-observer mean difference of 0.1 ± 11.0.
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