Why the study?
Does liver resection improve survival in patients with primary hepatic angiosarcoma?
Does liver resection improve survival in patients with primary hepatic angiosarcoma?
Curative liver resection for primary hepatic angiosarcoma can achieve 5-year survival rates of 40%.
May support resection in select cases; leaves open survival benefit in primary hepatic angiosarcoma.
OBJECTIVE: The aim of this study was to define the clinical features and surgical treatment outcomes of patients with primary hepatic angiosarcoma. METHODS: Data of the 6 patients diagnosed with primary hepatic angiosarcoma in Tianjin Medical University Cancer Institute and Hospital from January 1999 to December 2005 were retrospectively reviewed. RESULTS: The median age of the patients was 49 years (range 45-78 years) with a male predominance. Laboratory tests showed a mild elevation of α-fetoprotein in 2 patients, and 2 had both hepatitis B and C. Liver resection was performed in all patients. For the 5 patients who received curative liver resection, the median follow-up duration was 41 months (range 23-84 months) and the overall 1-year, 3-year and 5-year survival rates were 100.0%, 80.0% and 40.0%, respectively. One patient who underwent a palliative operation died of tumor progression a month after operation. CONCLUSION: Early diagnosis is necessary and complete surgical resection is the key to improve prognosis.
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Duan et al. (2012) studied this question.
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