Key result
Central systolic blood pressure was a stronger predictor of cardiovascular disease events than brachial blood pressure, with a hazard ratio of 1.49 per 1-standard deviation increment.
Why the study?
The study was conducted to evaluate the association of blood pressure measurements with cardiovascular disease risk and examine whether central systolic blood pressure predicts cardiovascular disease better than brachial blood pressure measurements.
Does non-invasively estimated central systolic blood pressure predict cardiovascular disease events better than brachial blood pressure measurements in a middle-aged Chinese population?
Cohort (n=8,710)
Yes
Does non-invasively estimated central systolic blood pressure predict cardiovascular disease events better than brachial blood pressure measurements in a middle-aged Chinese population?
Hazard Ratio: 1.49 (95% CI 1.31–1.7)
p-value: p=<0.001
Non-invasively estimated central systolic blood pressure is a stronger predictor of cardiovascular events than traditional brachial blood pressure measurements, particularly in women and high-risk individuals.
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Central SBP may add to brachial BP for CVD risk assessment in middle-aged adults; leaves open whether it improves clinical risk stratification.
Dong et al. (2020) conducted a cohort in Cardiovascular disease risk (n=8,710). Central systolic blood pressure (CSBP) vs. Brachial blood pressure (SBP and PP) was evaluated on First cardiovascular disease (CVD) events (HR 1.49, 95% CI 1.31-1.70, p=<0.001). Central systolic blood pressure was a stronger predictor of cardiovascular disease events than brachial blood pressure, with a hazard ratio of 1.49 per 1-standard deviation increment.
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