Blue fluorescence is exhibited by the hexaazakekulene 1, the first fully aromatic heteroanalogue of kekulene. It was synthesized in four steps from formaldehyde and proflavine (3,6-diaminoacridine). Although 1 is insoluble in organic solvents, it is slightly soluble in strong acids such as methanesulfonic or trifluoroacetic acid—probably due to protonation.
No takes yet. Share an insight, caveat, or question.
Tatibouët et al. (1997) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: