Key result
Patients newly diagnosed with atrial fibrillation reported lower symptom burden (P=0.004) and better health-related quality of life (P=0.015) at 6 months compared to those previously diagnosed.
Why the study?
To compare patient-reported outcomes in patients newly diagnosed with atrial fibrillation with those who have had a longer diagnosis, and to investigate whether these outcomes change over 6 months.
Do patient-reported outcomes differ between patients newly diagnosed with atrial fibrillation and those with a longer diagnosis over a 6-month period?
Cohort (n=129)
Do patient-reported outcomes differ between patients newly diagnosed with atrial fibrillation and those with a longer diagnosis over a 6-month period?
Patients newly diagnosed with atrial fibrillation report more positive patient-reported outcomes and better quality of life over 6 months compared to those with a longer-standing diagnosis, highlighting a window for early supportive intervention.
AIMS: To compare patient-reported outcomes (PROs) in patients newly (<6 months) diagnosed with atrial fibrillation (AF) with those who have had a longer diagnosis (≥6 months) and to investigate whether or not these outcomes change over a 6-month period. METHODS AND RESULTS: In this longitudinal survey study, 129 patients with AF completed the Revised Illness Perception Questionnaire, the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia, and the Hospital Anxiety and Depression Scale at baseline and after 6 months. At baseline, patients newly diagnosed with AF (n = 53), compared with patients with a previous diagnosis (n = 76), reported AF as more temporary (P = 0.003) and had a higher belief in personal and treatment control (P = 0.004 and P = 0.041, respectively). At a 6-month follow-up, patients newly diagnosed reported a lower symptom burden (P = 0.004), better health-related quality of life (HRQoL); (P = 0.015), and a higher personal control (P < 0.001) than patients previously diagnosed. Over time, in patients newly diagnosed, symptom burden and the anxiety symptom score decreased (P = 0.001 and P = 0.014, respectively) and HRQoL improved (P = 0.002). CONCLUSION: Patients newly diagnosed with AF reported more positive PROs both at baseline and at a 6-month follow-up than patients with a previous diagnosis of AF. Therefore, it is important to quickly capture patients newly diagnosed to support their belief in their own abilities. Such support may, alongside medical treatments, help patients manage the disease, which may lead to reduced symptom burden and better HRQoL over time.
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Holmlund et al. (2024) conducted a cohort in Atrial fibrillation (n=129). Newly diagnosed atrial fibrillation (<6 months) vs. Previously diagnosed atrial fibrillation (≥6 months) was evaluated on Patient-reported outcomes including symptom burden, health-related quality of life, and personal control. Patients newly diagnosed with atrial fibrillation reported lower symptom burden (P=0.004) and better health-related quality of life (P=0.015) at 6 months compared to those previously diagnosed.
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