Key result
This review outlines clinical warning signs, interfering conditions, and available screening tests for cognitive impairment in patients with chronic kidney disease.
Why the study?
Neurocognitive disorders are frequent among CKD patients, and identifying cognitive impairment can guide management, but various CKD-related conditions can influence cognitive assessment results.
This review highlights the importance of identifying and characterizing cognitive impairment in CKD patients to improve adherence, modify pharmacotherapy, and provide appropriate support.
Identifying CI in CKD may aid adherence assessment and reversible cause detection; leaves open standardized screening protocols for routine care.
Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.
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Pépin et al. (2021) conducted a review in Chronic kidney disease and cognitive disorders. Clinical assessment of cognitive disorders was evaluated. This review outlines clinical warning signs, interfering conditions, and available screening tests for cognitive impairment in patients with chronic kidney disease.
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