A color-changed sandwich: A novel water-soluble cyclophane containing anthracene and imidazolium moieties (see structure) exhibits dual emission in aqueous medium and undergoes sequence-selective interactions with DNA but not with proteins and micelles. In the presence of DNA, it forms a sandwich-type excimer, which exhibits an unusually long lifetime (τ) and red-shifted emission. This cyclophane can be used for DNA recognition through “turned on” excimer emission.
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Neelakandan et al. (2008) studied this question.
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