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August 1, 1989Biochemical JournalOpen Access

The novel thermogenic β-adrenergic agonist Ro 16-8714 increases the interscapular brown-fat β-receptor-adenylate cyclase and the uncoupling-protein mRNA level in obese (fa/fa) Zucker rats

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Authors

PMPatrick MuzzinUniversity of GenevaJRJ P RevelliCentre National de la Recherche ScientifiqueDRDaniel RicquierInstitut Cochin

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Muzzin et al. (1989) studied this question.

synapsesocial.com/papers/6a871cfecbc6304817befccdhttps://doi.org/10.1042/bj2610721
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein.1985 · 246 citations
  2. 2Alterations of Brown Adipose Tissue in Genetically Obese (ob/ob) Mice, II. Studies of β-Adrenergic Receptors and Fatty Acid Degradation*1982 · 20 citations
  3. 3The effect of adrenalectomy on GDP binding to brown-adipose-tissue mitochondria of obese rats1982 · 102 citations
  4. 4Abnormal brown adipose composition and beta-adrenoceptor binding in obese Zucker rats1982 · 17 citations
  5. 5Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline1978 · 652 citations