Population
Cardiac patients and healthy humans (general discussion on Type D personality)
Design
Review
Authors
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Cortisol reactivity may mediate Type D-CHD link; hypothesis-generating and requires prospective causal studies before clinical consideration.
Type D personality may increase the risk of coronary heart disease through elevated cortisol reactivity to stress.
Leo Sher (2005) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: