Why the study?
Does argatroban provide safe and effective anticoagulation in adults undergoing cardiac surgery?
Population
21 reported cases of adults undergoing cardiac surgery (15 off-pump, 6 on-pump)
Design
Case_series
Authors
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Argatroban in cardiac surgery requires tailored ACT monitoring to balance thrombosis and coagulopathy risks; case reports leave open its comparative safety versus heparin.
Does argatroban provide safe and effective anticoagulation in adults undergoing cardiac surgery?
Argatroban can be used for anticoagulation during cardiac surgery, but requires careful ACT monitoring to balance the risks of thrombosis and severe coagulopathy, particularly during on-pump procedures.
Kloecker et al. (2006) studied this question.
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