Novel Troponin Fragmentation Assay to Discriminate Between Troponin Elevations in Acute Myocardial Infarction and End-Stage Renal Disease

“More than half of the small troponin elevations detected in emergency department patients are due to causes other than heart attack. The developed test seems to separate very well the small troponin elevations caused by threatening MI from more benign transient troponin elevations.”

Saara WittfoothAssociate Professor of Biotechnology, University of Turku

“A special feature of the test we have developed is that it would be possible to implement it in automated analysis systems in the hospital laboratories, similarly as the commercial troponin tests currently at use in the hospital laboratories.”

Saara WittfoothAssociate Professor of Biotechnology, University of Turku

“Our investigations with large patient cohorts are still ongoing but it seems that long cardiac troponin T could be especially useful in identifying mild cardiac infarction and the settings where the current assays are showing elevated results. For example, when the patient has reduced renal function, when the patient has atrial fibrillation, or if the patient has been doing heavy exercise.”