The syntheses of four ACTH‐analogues: [Orn 15‐18 ]‐, [ D Ser 1 , Orn 15‐18 ]‐, [Orn 11‐15‐18 ]‐ and [ D Ser 1 , Orn 11,15‐18 ]‐β‐corticotropin‐(1‐18)‐octadecapeptide amide** are described. The last mentioned compound exhibits an unexpected, strongly prolonged, biological activity. A possible explanation is given.
No takes yet. Share an insight, caveat, or question.
Tesser et al. (1971) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: