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June 19, 1990Biochemistry

Effect of ADP on the orientation of spin-labeled myosin heads in muscle fibers: a high-resolution study with deuterated spin labels

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Authors

PFPiotr G. FajerFlorida State UniversityEFElizabeth A. FajerFlorida State UniversityJMJohn J. MattaUniversity of Minnesota

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Implication

ADP effects on myosin orientation warrant caution extrapolating to cardiac muscle; leaves open role in heart failure models.

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Cite This Study

Fajer et al. (1990) studied this question.

synapsesocial.com/papers/6a87a4c87ef8b32fd3f3e763https://doi.org/10.1021/bi00476a031
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Binding of myosin to actin in myofibrils during ATP hydrolysis1989 · 23 citations
  2. 2Kinetics of the interaction between actin, ADP, and cardiac myosin-S1.1984 · 190 citations
  3. 3On the molecular basis for chemomechanical energy transduction in muscle.1979 · 42 citations
  4. 4Fluorescent modification and orientation of myosin sulfhydryl 2 in skeletal muscle fibers1989 · 38 citations
  5. 5Tryptic digestion of rabbit skeletal myofibrils: an enzymatic probe of myosin cross-bridges1984 · 22 citations