Why the study?
The study was conducted to explore the aetiologies underlying Perthes disease and examine recent incidence trends to evaluate potential links between incidence rates and specific causative factors.
Population
23 articles on Perthes disease
Design
Systematic review conducted in accordance with PRISMA guidelines
Authors
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Supports perinatal public health measures; confirms multifactorial etiology via systematic review of trends.
The declining incidence of Perthes disease appears to be multifactorial, strongly correlating with positive economic and environmental changes.
Ibrahim et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: