Why the study?
Are heritable thrombophilic mutations associated with Legg-Perthes disease in children?
Population
90 children diagnosed with Perthes' disease and 200 healthy donors as a control group
Comparison
Heritable thrombophilic mutations vs Healthy donors without Perthes' disease
Design
Case-control
Authors
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No association with these thrombophilic variants; leaves open their role in Perthes' disease pathogenesis pending larger studies.
Are heritable thrombophilic mutations associated with Legg-Perthes disease in children?
Screening for heritable thrombophilic mutations is not supported in children with Legg-Perthes disease, as there is no significant association.
López-Franco et al. (2005) studied this question.
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