Why the study?
Are individual blood pressure components associated with eGFR decline in patients with late-stage CKD?
Population
1,203 patients with late-stage CKD (eGFR ≤30) managed in a multidisciplinary CKD clinic.
Comparison
Time-varying systolic blood pressure, diastolic… vs Referent blood pressure ranges
Design
Cohort
Follow-up
median 548 days
Authors
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Suggests optimal BP targets may be narrow in late-stage CKD; leaves open whether strict.
Are individual blood pressure components associated with eGFR decline in patients with late-stage CKD?
In patients with late-stage CKD, extremes of systolic BP and elevated diastolic BP are associated with accelerated eGFR decline, suggesting optimal BP targets may be narrow in this population.
Sood et al. (2017) studied this question.
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