Why the study?
Does strict blood pressure control (SBP <120 mm Hg) reduce all-cause mortality compared to conventional control (SBP 120-139 mm Hg) in patients with chronic kidney disease?
Population
n=77,765 US veterans with prevalent chronic kidney disease and uncontrolled hypertension, who received 1 or…
Comparison
Strict blood pressure control achieving a… vs Conventional blood pressure control achieving a…
Design
Cohort
Follow-up
median 6.0 years
Authors
Loading...
Strict SBP <120 mm Hg was associated with higher mortality in CKD; hypothesis-generating and should not yet change practice.
Does strict blood pressure control (SBP <120 mm Hg) reduce all-cause mortality compared to conventional control (SBP 120-139 mm Hg) in patients with chronic kidney disease?
In a large observational cohort of US veterans with CKD, strict systolic blood pressure control (<120 mm Hg) was associated with a significantly higher risk of all-cause mortality compared to conventional control (120-139 mm Hg).
Kövesdy et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: