Key result
In a meta-analysis of 15,924 patients with nondialysis-dependent chronic kidney disease, more intensive blood pressure therapies generally reduced mortality in all subgroups.
Why the study?
Does intensive blood pressure management reduce cardiovascular events and mortality in persons with nondialysis-dependent chronic kidney disease?
Population
Persons with nondialysis-dependent chronic kidney disease (CKD)
Comparison
Intensive blood pressure management vs Standard blood pressure management
Design
Review
Authors
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Supports intensive BP control to reduce mortality in nondialysis CKD; confirms consistency across subgroups.
Does intensive blood pressure management reduce cardiovascular events and mortality in persons with nondialysis-dependent chronic kidney disease?
Disparate findings between trials and observational studies regarding optimal BP in CKD may stem from differences in patient characteristics and BP measurement techniques.
Walther et al. (2017) conducted a review in nondialysis-dependent chronic kidney disease. Intensive blood pressure control vs. Standard blood pressure control was evaluated on mortality. In a meta-analysis of 15,924 patients with nondialysis-dependent chronic kidney disease, more intensive blood pressure therapies generally reduced mortality in all subgroups.
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